Article

Identifying the spatial and temporal dynamics of molecularly-distinct glioblastoma sub-populations

2020-04-08

Abstract excerpt

Glioblastomas (GBMs) are the most aggressive primary brain tumours and have no known cure. Each individual tumour comprises multiple sub-populations of genetically-distinct cells that may respond differently to targeted therapies and may contribute to disappointing clinical trial results. Image-localized biopsy techniques allow multiple biopsies to be taken during surgery and provide information that identifies re...

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Literature Corpus work: 925ba1d9-d57f-5e73-aaaa-bc037b4e821d
DOI: 10.1101/2020.04.08.024091

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