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Article

Targeting adaptive glioblastoma: an overview of proliferation and invasion

30 Jul 2014

Abstract excerpt

Glioblastoma is one of the most devastating cancers, in which tumor cell infiltration into surrounding normal brain tissue confounds clinical management. This review describes basic and translational research into glioma proliferation and invasion, in particular the phenotypic switch underlying a stochastic "go or grow" model of tumor cell behavior. We include recent progress in system genomics, cancer stem cell...

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PMID: 25082799
DOI: 10.1093/neuonc/nou147

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