Article
Myeloid-Derived Suppressor Cells: New Insights into the Pathogenesis and Therapy of MDS
21 Aug 2022
Abstract excerpt
Myelodysplastic syndromes (MDS) are hematopoietic malignancies characterized by the clonal expansion of hematopoietic stem cells, bone marrow failure manifested by cytopenias, and increased risk for evolving to acute myeloid leukemia. Despite the fact that the acquisition of somatic mutations is considered key for the initiation of the disease, the bone marrow microenvironment also plays significant roles in MDS...
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