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Article

New Insights into the Pathogenesis of MDS and the rational therapeutic opportunities.

Expert review of hematology - 1 Jan 2016

Abou Zahr Abdallah, Bernabe Ramirez Carolina, Wozney Jocelyn, Prebet Thomas, Zeidan Amer M

Abstract excerpt

Myelodysplastic syndromes (MDS) include a heterogeneous group of acquired hematopoietic malignancies characterized by ineffective hematopoiesis, peripheral cytopenias, and a varying propensity for progression to acute myeloid leukemia. The clinical heterogeneity in MDS is a reflection of its molecular heterogeneity. Better understanding of aberrant epigenetics, dysregulation of immune responses, and del(5q) MDS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26734762
DOI: 10.1586/17474086.2016.1135047

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