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Article

Insight into the molecular pathophysiology of myelodysplastic syndromes: targets for novel therapy.

European journal of haematology - 1 Oct 2016

Zahid Mohammad Faizan, Patnaik Mrinal M, Gangat Naseema, Hashmi Shahrukh K, Rizzieri David A

Abstract excerpt

Myelodysplastic syndromes (MDS) are clonal hematopoietic stem cell disorders characterized by abnormal cellular differentiation and maturation with variable progression to acute leukemia. Over the last decade, scientific discoveries have unraveled specific pathways involved in the complex pathophysiology of MDS. Prominent examples include aberrations in cytokines and their signaling pathways (such as tumor...

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Source

Identifiers

PMID: 27147278
DOI: 10.1111/ejh.12771

Genes

ASXL1
SRSF2
TET2
ZRSR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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