Article

Mesenchymal Stem Cells in Myelodysplastic Syndromes and Leukaemia Microenvironment

2024-07-01

Abstract excerpt

Mesenchymal stem cells (MSCs) are one of the main residents in the bone marrow (BM), having an essential role in the regulation of hematopoietic stem cell (HSCs) differentiation and proliferation. Myelodysplastic syndromes (MDS) are a group of myeloid disorders impacting hematopoietic stem and progenitor cells (HSCPs) and characterised by BM failure, ineffective haematopoiesis, cytopenia, a high risk of transforma...

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Literature Corpus work: 13ed4c45-294a-5503-ba2f-210ec8ac245d
DOI: 10.20944/preprints202406.1958.v1

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