Prognostic Analysis of the IDH1 G105G (rs11554137) SNP in IDH-Wildtype Glioblastoma.

doi:10.3390/genes13081439

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Prognostic Analysis of the IDH1 G105G (rs11554137) SNP in IDH-Wildtype Glioblastoma.

Genes - 12 Aug 2022

Saaid Ayoub, Monticelli Matteo, Ricci Alessia Andrea, Orlando Giulia, Botta Cristina, Zeppa Pietro, Bianconi Andrea, Osella-Abate Simona, Bruno Francesco, Pellerino Alessia, Rudà Roberta, Cassoni Paola, Garbossa Diego, Cofano Fabio, Bertero Luca

Abstract excerpt

The G105G SNP (rs11554137) in the IDH1 gene is observed in about 10-15% of patients with a diffuse glioma. Data regarding its impact on gliomas are poor and partially conflicting, possibly due to the evolving classification of CNS tumors. The aim of this study was to investigate the G105G SNP prognostic significance in a homogenous cohort of IDH-wildtype glioblastomas, in agreement with the 2021 WHO...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioblastoma

Share to Glioma

Share to Glioma Diagnosis and Treatment

Share to Isocitrate Dehydrogenase

Share to Mutation

Share to Polymorphism, Single Nucleotide

Share to Prognosis

Source

Open in PubMed Open full text

Identifiers

PMID: 36011350
DOI: 10.3390/genes13081439
PMCID: PMC9408597

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prognostic Analysis of the IDH1 G105G (rs11554137) SNP in IDH-Wildtype Glioblastoma.PMID 36011350Read ↗

Prognostic impact of the isocitrate dehydrogenase 1 single-nucleotide polymorphism rs11554137 in malignant gliomas.Semantic proximity Read ↗

Clinical prognostic value of the isocitrate dehydrogenase 1 single-nucleotide polymorphism rs11554137 in glioblastoma.Semantic proximity Read ↗

IDH1105GGT single nucleotide polymorphism improves progression free survival in patients with IDH mutated grade II and III gliomas.Semantic proximity Read ↗

Prevalence of the single-nucleotide polymorphism rs11554137 (IDH1105GGT) in brain tumors of a cohort of Italian patients.Semantic proximity Read ↗

Understanding the IDH1 missense SNPs on expression of genes involved in Glioblastoma multiforme.Semantic proximity Read ↗

PTPN11 variant may be a prognostic indicator of IDH-wildtype glioblastoma in a comprehensive genomic profiling cohort.Semantic proximity Read ↗

Clinicopathological and molecular landscape of 5-year IDH-wild-type glioblastoma survivors: A multicentric retrospective study.Semantic proximity Read ↗

Prognostic significance of IDH 1 mutation in patients with glioblastoma multiforme.Semantic proximity Read ↗

Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis.Semantic proximity Read ↗

Isocitrate Dehydrogenase Mutations are Better Prognostic Marker than O6-methylguanine-DNA Methyltransferase Promoter Methylation in Glioblastomas - a Retrospective, Single-centre Molecular Genetics Study of Gliomas.Semantic proximity Read ↗

The Influence of Gene Aberrations on Survival in Resected IDH Wildtype Glioblastoma Patients: A Single-Institution Study.Semantic proximity Read ↗

Impact of IDH mutation and MGMT methylation as Independent prognostic markers in uniformly treated high grade glioma Patients: A Real-World evidence in the Indian Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.