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Article

Clinical prognostic value of the isocitrate dehydrogenase 1 single-nucleotide polymorphism rs11554137 in glioblastoma.

Journal of neuro-oncology - 1 Jun 2018

Mistry Akshitkumar M, Vnencak-Jones Cindy L, Mobley Bret C

Abstract excerpt

The presence of the single-nucleotide polymorphism (SNP) rs11554137:C>T in the IDH1 gene is associated with a significantly lower survival in acute myeloid leukemia patients. The impact of its presence in glioblastoma on patient survival is unclear. We retrospectively reviewed 171 adult (> 18 years of age) patients treated at a single, tertiary academic center for supratentorial glioblastoma (WHO grade IV)...

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Identifiers

PMID: 29423539
DOI: 10.1007/s11060-018-2796-6

Genes

IDH1
IDH2
MGMT

Provenance

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