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Article

Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis.

Acta neuropathologica - 1 Dec 2010

Metellus Philippe, Coulibaly Bema, Colin Carole, de Paula Andre Maues, Vasiljevic Alexandre, Taieb David, Barlier Anne, Boisselier Blandine, Mokhtari Karima, Wang Xiao Wei, Loundou Anderson, Chapon Frederique, Pineau Sandrine, Ouafik L'Houcine, Chinot Olivier, Figarella-Branger Dominique

Abstract excerpt

The phenotypic heterogeneity of low-grade gliomas (LGGs) is still inconsistently explained by known molecular abnormalities in patients treated according to the present standards of care. IDH1 codon 132 and IDH2 codon 172 sequencing was performed in a series of 47 LGGs and correlated with clinica...

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Source

Identifiers

PMID: 21080178
DOI: 10.1007/s00401-010-0777-8

Genes

IDH1
IDH2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21080178-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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