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Article

The Influence of Gene Aberrations on Survival in Resected IDH Wildtype Glioblastoma Patients: A Single-Institution Study.

Current oncology (Toronto, Ont.) - 21 Mar 2021

Kalita Ondrej, Sporikova Zuzana, Hajduch Marian, Megova Houdova Magdalena, Slavkovsky Rastislav, Hrabalek Lumir, Halaj Matej, Klementova Yvona, Dolezel Martin, Drabek Jiri, Tuckova Lucie, Ehrmann Jiri, Vrbkova Jana, Trojanec Radek, Vaverka Miroslav

Abstract excerpt

This prospective population-based study on a group of 132 resected IDH-wildtype (IDH-wt) glioblastoma (GBM) patients assesses the prognostic and predictive value of selected genetic biomarkers and clinical factors for GBM as well as the dependence of these values on the applied therapeutic modalities. The patients were treated in our hospital between June 2006 and June 2015. Clinical data and tumor samples were...

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Brain Neoplasms
DNA Methylation
DNA Modification Methylases
Glioblastoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Glioma Diagnosis and Treatment

Isocitrate Dehydrogenase

MicroRNA in disease regulation

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Identifiers

PMID: 33801093
DOI: 10.3390/curroncol28020122
PMCID: PMC8025822

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