Prognostic impact of the isocitrate dehydrogenase 1 single-nucleotide polymorphism rs11554137 in malignant gliomas.

doi:10.1002/cncr.27798

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Article

Prognostic impact of the isocitrate dehydrogenase 1 single-nucleotide polymorphism rs11554137 in malignant gliomas.

Cancer - 15 Feb 2013

Wang Xiao-Wei, Boisselier Blandine, Rossetto Marta, Marie Yannick, Idbaih Ahmed, Mokhtari Karima, Gousias Konstantinos, Hoang-Xuan Khê, Delattre Jean-Yves, Simon Matthias, Labussière Marianne, Sanson Marc

Abstract excerpt

BACKGROUND: The IDH1 gene, which encodes isocitrate dehydrogenase 1, is frequently mutated in gliomas and acute myeloid leukemia. The single-nucleotide polymorphism (SNP) (reference SNP no. rs11554137:C>T) located on IDH1 codon 105 has been associated with a poor outcome in patients with acute my...

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PMID: 23184331
DOI: 10.1002/cncr.27798

Genes

IDH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23184331-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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