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Bulk segregant linkage mapping for rodent and human malaria parasites

22 Aug 2022

Abstract excerpt

In 2005 Richard Carter's group surprised the malaria genetics community with an elegant approach to rapidly mapping the genetic basis of phenotypic traits in rodent malaria parasites. This approach, which he termed "linkage group selection", utilized bulk pools of progeny, rather than individual clones, and exploited simple selection schemes to identify genome regions underlying resistance to drug treatment (or...

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PMID: 36007706
DOI: 10.1016/j.parint.2022.102653

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