Article
Linkage group selection: rapid gene discovery in malaria parasites.
Genome research - 1 Jan 2005
Culleton Richard, Martinelli Axel, Hunt Paul, Carter Richard
Abstract excerpt
The identification of parasite genes controlling phenotypes such as drug resistance, virulence, immunogenicity, and transmission is vital to malaria research. Classical genetic methods have achieved these goals only rarely and with difficulty. We describe here a novel genetic method, Linkage Group Selection (LGS), which achieves rapid de novo location of genes encoding selectable phenotypes of malaria parasites....
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