Article
Analysis of malaria parasite phenotypes using experimental genetic crosses of Plasmodium falciparum.
International journal for parasitology - 15 May 2012
Ranford-Cartwright Lisa C, Mwangi Jonathan M
Abstract excerpt
We review the principles of linkage analysis of experimental genetic crosses and their application to Plasmodium falciparum. Three experimental genetic crosses have been performed using the human malaria parasite P. falciparum. Linkage analysis of the progeny of these crosses has been used to identify parasite genes important in phenotypes such as drug resistance, parasite growth and virulence, and transmission...
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