Article
TLR10 genotypes affect long-term graft function in tacrolimus-treated solid organ transplant recipients.
International immunopharmacology - 1 Oct 2022
Xu Qinxia, Dong Yue, Niu Wanjie, Zheng Xinyi, Li Ruidong, Zhang Ming, Wang Zhengxin, Qiu Xiaoyan
Abstract excerpt
The present study was conducted to investigate the relationship between single nucleotide polymorphisms (SNPs) in TLR10 and the clinical outcomes of renal transplant patients who took tacrolimus (TAC) as an immunosuppressant, and further confirmed the results in liver transplant patients. A total of 172 renal transplant patients and 145 pairs of liver transplant recipients and donors were included. Nineteen SNPs...
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