Article
Significant Association between Toll-Like Receptor Gene Polymorphisms and Posttransplantation Diabetes Mellitus.
Nephron - 1 Jan 2016
Kim Jin Sug, Kim Seul Ki, Park Ji Yoon, Kim Yang Gyun, Moon Joo Young, Lee Sang Ho, Ihm Chun Gyoo, Lee Tae Won, Kim Su Kang, Chung Joo-Ho, Kang Sun Woo, Kim Tae Hee, Kim Yeong Hoon, Jeong Kyung Hwan
Abstract excerpt
BACKGROUND: Posttransplantation diabetes mellitus (PTDM) is an important metabolic complication after renal transplantation. Activation of the innate immune system via toll-like receptors (TLRs) is implicated in the pathogenesis of insulin resistance and deficiency. Although links between diabetes, dysregulated innate immune responses, and the TLR signaling pathway have been reported, no study so far has...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
