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Pharmacogenetic analysis of interleukin-10 variants and tacrolimus metabolism in kidney transplant patients from Pakistani population.

Molecular biology reports - 31 Aug 2024

Batool Tuba, Ahmad Fareeha, Bashir Rasheeda, Rafaqat Sana

Abstract excerpt

BACKGROUND: End stage renal disease (ESRD) occurs when the kidneys are unable to filter the waste products and excessive fluids from the blood that results into the accumulation of toxins and fluid in the body. Tacrolimus is commonly used immunosuppressant while sirolimus and cyclosporin are rarely used drugs to stop solid organ transplant rejection. The host's immunological response following transplantation...

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PMID: 39215891
DOI: 10.1007/s11033-024-09873-z

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