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Article

Mobile Translation Systems Generate Genomically Engineered Escherichia coli Cells with Improved Growth Phenotypes.

ACS synthetic biology - 16 Sept 2022

Gowland Samuel, Jewett Michael C

Abstract excerpt

Cellular translation is responsible for the synthesis of proteins, a highly diverse class of macromolecules that form the basis of biological function. In Escherichia coli, harnessing and engineering of the biomolecular components of translation, such as ribosomes, transfer RNAs (tRNAs), and aminoacyl-tRNA synthetases, has led to both biotechnology products and an expanded genetic code. However, the engineering...

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PMID: 35951371
DOI: 10.1021/acssynbio.2c00099
PMCID: PMC9990117

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