Article

Genetically encoded RNA strand exchange circuits for programmable protein expression and computation in cells

2025-09-24

Abstract excerpt

Programmable cellular information processing could advance biomanufacturing of chemicals and medicine, and enable smart, living therapeutics and diagnostics. Nucleic acids circuits based on toehold mediated strand exchange (TMSE) show tremendous potential for cellular programming due to their scalable, composable, and biocompatible parts. However, these circuits are constrained primarily to in vitro applications b...

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Literature Corpus work: 2f754013-af80-54b3-bf46-9914ae2dfd80
DOI: 10.1101/2025.09.24.678369

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