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Sirtuins and cognition: implications for learning and memory in neurological disorders

22 Jul 2022

Abstract excerpt

-dependent manner. The mammalian family of sirtuins is composed of seven histone deacetylase and ADP-ribosyltransferase proteins (SIRT1-SIRT7) that are found throughout the different cellular compartments of the cell. Sirtuins in the brain have received considerable attention in cognition due to their role in a plethora of metabolic and age-related diseases and their ability to induce neuroprotection. More...

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PMID: 35936890
DOI: 10.3389/fphys.2022.908689

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