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Sirtuin Proteins and Memory: A Promising Target in Alzheimer’s Disease Therapy?

27 Nov 2024

Abstract excerpt

Sirtuins (SIRTs), nicotine adenine dinucleotide (+)-dependent histone deacetylases, have emerged as critical regulators in many signalling pathways involved in a wide range of biological processes. Currently, seven mammalian SIRTs have been characterized and are found across a number of cellular compartments. There has been considerable interest in the role of SIRTs in the brain due to their role in a plethora of...

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PMID: 39683482
DOI: 10.3390/nu16234088

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