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Article

Discovery of nonautonomous modulators of activated Ras.

G3 (Bethesda, Md.) - 30 Sept 2022

Corchado-Sonera Marcos, Rambani Komal, Navarro Kristen, Kladney Raleigh, Dowdle James, Leone Gustavo, Chamberlin Helen M

Abstract excerpt

Communication between mesodermal cells and epithelial cells is fundamental to normal animal development and is frequently disrupted in cancer. However, the genes and processes that mediate this communication are incompletely understood. To identify genes that mediate this communication and alter the proliferation of cells with an oncogenic Ras genotype, we carried out a tissue-specific genome-wide RNAi screen in...

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PMID: 35929788
DOI: 10.1093/g3journal/jkac200
PMCID: PMC9526067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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