Article
Analysis of rare driving events in pediatric acute myeloid leukemia.
Haematologica - 1 Jan 2023
Noort Sanne, Oosterwijk Jolieke van, Ma Jing, Garfinkle Elizabeth A R, Nance Stephanie, Walsh Michael, Song Guangchun, Reinhardt Dirk, Pigazzi Martina, Locatelli Franco, Hasle Henrik, Abrahamsson Jonas, Jarosova Marie, Kelaidi Charikleia, Polychronopoulou Sophia, Van den Heuvel-Eibrink Marry M, Fornerod Maarten, Gruber Tanja A, Zwaan C Michel
Abstract excerpt
Elucidating genetic aberrations in pediatric acute myeloid leukemia (AML) provides insight in biology and may impact on risk-group stratification and clinical outcome. This study aimed to detect such aberrations in a selected series of samples without known (cyto)genetic aberration using molecular profiling. A cohort of 161 patients was selected from various study groups: DCOG, BFM, SJCRH, NOPHO and AEIOP....
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