Article
Updates in molecular genetics of acute myeloid leukemia.
Seminars in diagnostic pathology - 1 May 2023
Kurzer Jason H, Weinberg Olga K
Abstract excerpt
Acute myeloid leukemia (AML) is a type of cancer caused by aggressive neoplastic proliferations of immature myeloid cells that is fatal if untreated. AML accounts for 1.0% of all new cancer cases in the United States, with a 5-year relative survival rate of 30.5%. Once defined primarily morphologically, advances in next generational sequencing have expanded the role of molecular genetics in categorizing the...
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