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Article

Neuroimmune dysfunction in frontotemporal dementia: Insights from progranulin and C9orf72 deficiency.

Current opinion in neurobiology - 1 Oct 2022

Hashimoto Kei, Jahan Naznin, Miller Zachary A, Huang Eric J

Abstract excerpt

Neuroimmune dysfunction is a cardinal feature of neurodegenerative diseases. But how immune dysregulation in the brain and peripheral organs contribute to neurodegeneration remains unclear. Here, we discuss the recent advances highlighting neuroimmune dysfunction as a key disease-driving factor in frontotemporal dementia (FTD). We provide an overview of the clinical observations supporting a high prevalence of...

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Identifiers

PMID: 35792478
DOI: 10.1016/j.conb.2022.102599
PMCID: PMC9798541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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