Article
Dementia risk genes engage gene networks poised to tune the immune response towards chronic inflammatory states
2019-04-04
Abstract excerpt
An emerging challenge in neurodegenerative dementia is understanding how immune-associated genes and pathways contribute to disease. To achieve a refined view of neuroinflammatory signaling across neurodegeneration, we took an integrative functional genomics approach to consider neurodegeneration from the perspective of microglia and their interactions with other cells. Using large-scale gene expression and pertur...
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Identifiers and source
- Literature Corpus work
- c66b6912-9163-526d-b596-b606021bdb94
- DOI
- 10.1101/597542