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Article

Polygenic scores for schizophrenia and major depression are associated with psychosocial risk factors in children: evidence of gene-environment correlation.

Journal of child psychology and psychiatry, and allied disciplines - 1 Oct 2022

Machlitt-Northen Sandra, Keers Robert, Munroe Patricia B, Howard David M, Trubetskoy Vassily, Pluess Michael

Abstract excerpt

BACKGROUND: Whilst genetic and environmental risk factors for schizophrenia (SCZ) and major depressive disorder (MDD) have been established, it is unclear whether exposure to environmental risk factors is genetically confounded by passive, evocative or active gene-environment correlation (rGE). STUDY OBJECTIVE: This study aims to investigate: (a) whether the genetic risk for SCZ/MDD in children is correlated with...

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Identifiers

PMID: 35781881
DOI: 10.1111/jcpp.13657
PMCID: PMC9796489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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