Article
Phenotypic Manifestation of Genetic Risk for Schizophrenia During Adolescence in the General Population.
JAMA psychiatry - 1 Mar 2016
Jones Hannah J, Stergiakouli Evie, Tansey Katherine E, Hubbard Leon, Heron Jon, Cannon Mary, Holmans Peter, Lewis Glyn, Linden David E J, Jones Peter B, Davey Smith George, O'Donovan Michael C, Owen Michael J, Walters James T, Zammit Stanley
Abstract excerpt
IMPORTANCE: Schizophrenia is a highly heritable, polygenic condition characterized by a relatively diverse phenotype and frequent comorbid conditions, such as anxiety and depression. At present, limited evidence explains how genetic risk for schizophrenia is manifest in the general population. OBJECTIVE: To investigate the extent to which genetic risk for schizophrenia is associated with different phenotypes...
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