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Article

Widespread covariation of early environmental exposures and trait-associated polygenic variation.

Proceedings of the National Academy of Sciences of the United States of America - 31 Oct 2017

Krapohl E, Hannigan L J, Pingault J-B, Patel H, Kadeva N, Curtis C, Breen G, Newhouse S J, Eley T C, O'Reilly P F, Plomin R

Abstract excerpt

Although gene-environment correlation is recognized and investigated by family studies and recently by SNP-heritability studies, the possibility that genetic effects on traits capture environmental risk factors or protective factors has been neglected by polygenic prediction models. We investigated covariation between trait-associated polygenic variation identified by genome-wide association studies (GWASs) and...

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Source

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Identifiers

PMID: 29078306
DOI: 10.1073/pnas.1707178114
PMCID: PMC5676894

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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