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Article

Tumor-associated macrophages: A promising target for a cancer immunotherapeutic strategy.

Pharmacological research - 1 Nov 2020

Zhang Si-Yu, Song Xin-Yu, Li Yang, Ye Lin-Lin, Zhou Qiong, Yang Wei-Bing

Abstract excerpt

Macrophages, a type of myeloid immune cell, play essential roles in fighting against pathogenic invasion and activating T cell-mediated adaptive immune responses. As a major constituent of the tumor microenvironment (TME), macrophages play a complex role in tumorigenesis and tumor progression. They can inhibit tumor growth by releasing proinflammatory cytokines and exerting cytotoxic activities but principally...

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PMID: 33065284
DOI: 10.1016/j.phrs.2020.105111

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