Article
The Regulating Effect of CII-3 and Its Active Components from Periplaneta americana on M1/M2 Macrophage Polarization.
Molecules (Basel, Switzerland) - 10 Jul 2022
Xu Jinglei, Che Yihao, Liu Xinyue, Liu Chaohe, Meng Di, Pang Xiuqin, He Miao, Liu Guangming, Zhang Chenggui, Yang Dasong, Xiao Huai
Abstract excerpt
CII-3 is the effective part of Periplaneta americana for application in oncotherapy. This study investigated its main chemical components for macrophage polarization regulation activity. Compounds were separated and purified, and their structures were elucidated based on NMR and HR-ESI-MS analyses. After inducing the M1 and M2 phenotype macrophages, CII-3 and testing components were added and co-incubated to...
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