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Structure of the dengue virus RNA promoter

24 Jun 2022

Abstract excerpt

Dengue virus, a single-stranded positive sense RNA virus, is the most prevalent mosquito-borne pathogen in the world. Like all RNA viruses, it uses conserved structural elements within its genome to control essential replicative steps. A 70 nt stem-loop RNA structure (called SLA), found at the 5'-end of the genome of all flaviviruses, functions as the promoter for viral replication. This highly conserved...

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PMID: 35750488
DOI: 10.1261/rna.079197.122

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