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Article

NMR structure of Dengue West Nile viruses stem-loop B: A key cis-acting element for flavivirus replication.

Biochemical and biophysical research communications - 22 Oct 2020

Sharma Shrikant, Varani Gabriele

Abstract excerpt

Flaviviruses are major emerging human pathogenic viruses that pose a persistent and growing menace to global health. They are enveloped single-stranded RNA viruses with positive polarity transmitted by arthropod vectors like mosquitoes or ticks, responsible for a significant and growing number of human deaths and illnesses. The 5'- and 3'-untranslated regions (UTRs) are highly structured and contain conserved...

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Identifiers

PMID: 32807496
DOI: 10.1016/j.bbrc.2020.07.115
PMCID: PMC7494574

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