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Structure-first identification of RNA elements that regulate dengue virus genome architecture and replication

3 Apr 2023

Abstract excerpt

The genomes of RNA viruses encode the information required for replication in host cells both in their linear sequence and in complex higher-order structures. A subset of these RNA genome structures show clear sequence conservation, and have been extensively described for well-characterized viruses. However, the extent to which viral RNA genomes contain functional structural elements-unable to be detected by...

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PMID: 37011200
DOI: 10.1073/pnas.2217053120

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