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Functional RNA Elements in the Dengue Virus Genome

15 Sept 2011

Abstract excerpt

Dengue virus (DENV) genome amplification is a process that involves the viral RNA, cellular and viral proteins, and a complex architecture of cellular membranes. The viral RNA is not a passive template during this process; it plays an active role providing RNA signals that act as promoters, enhancers and/or silencers of the replication process. RNA elements that modulate RNA replication were found at the 5' and...

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PMID: 21994804
DOI: 10.3390/v3091739

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