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Distinct interactors define the p63 transcriptional signature in epithelial development or cancer

24 Jun 2022

Abstract excerpt

The TP63 is an indispensable transcription factor for development and homeostasis of epithelia and its derived glandular tissue. It is also involved in female germline cell quality control, muscle and thymus development. It is expressed as multiple isoforms transcribed by two independent promoters, in addition to alternative splicing occurring at the mRNA 3'-UTR. Expression of the TP63 gene, specifically the...

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PMID: 35748701
DOI: 10.1042/bcj20210737

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