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Article

Identification and functional characterization of two new transcriptional variants of the human p63 gene

21 Aug 2009

Abstract excerpt

p63 belongs to a family of transcription factors, which, while demonstrating striking conservation of functional domains, regulate distinct biological functions. Its principal role is in the regulation of epithelial commitment, differentiation and maintenance programs, during embryogenesis and in adult tissues. The p63 gene has a complex transcriptional pattern, producing two subclasses of N-terminal isoforms (TA...

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PMID: 19700772
DOI: 10.1093/nar/gkp674

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