Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Type 2 deiodinase p.Thr92Ala polymorphism does not affect the severity of obesity and weight loss after bariatric surgery.

Scientific reports - 23 Jun 2022

Benenati Nicoletta, Bufano Annalisa, Cantara Silvia, Ricci Claudia, Marzocchi Carlotta, Ciuoli Cristina, Sannino Ida, Tirone Andrea, Voglino Costantino, Vuolo Giuseppe, Castagna Maria Grazia

Abstract excerpt

A single nucleotide polymorphism in the Type 2 deiodinase (DIO2) gene (p.Thr92Ala) was found to be associated with hypertension, type 2 diabetes mellitus (T2DM), insulin resistance, and body mass index (BMI). We retrospectively evaluated 182 patients to assess whether the DIO2 p.Thr92Ala was associated with severe obesity and response to bariatric surgery. Genomic DNA was extracted from peripheral blood...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bariatric Surgery
Share to Hypertension

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Iodide Peroxidase

Share to Iodothyronine Deiodinase Type II

Share to Obesity, Morbid

Share to Polymorphism, Single Nucleotide

Share to Weight Loss

Source

Open in PubMed Open full text

Identifiers

PMID: 35739305
DOI: 10.1038/s41598-022-14863-x
PMCID: PMC9226046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Type 2 deiodinase p.Thr92Ala polymorphism does not affect the severity of obesity and weight loss after bariatric surgery.PMID 35739305Read ↗

Type 2 Deiodinase p.Thr92Ala polymorphism does not affect the severity of obesity and weight loss after bariatric surgerySemantic proximity Read ↗

The Type 2 Deiodinase Thr92Ala Polymorphism Is Associated with Higher Body Mass Index and Fasting Glucose Levels: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

The Type 2 Deiodinase Thr92Ala Polymorphism Is Associated with Worse Glycemic Control in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects.Semantic proximity Read ↗

Association Between a Novel Variant of the Human Type 2 Deiodinase Gene Thr92Ala and Insulin ResistanceSemantic proximity Read ↗

The Physiological Functions and Polymorphisms of Type II DeiodinaseSemantic proximity Read ↗

The rs225017 polymorphism in the 3'UTR of the human DIO2 gene is associated with increased insulin resistance.Semantic proximity Read ↗

Association of the type 2 deiodinase Thr92Ala polymorphism with type 2 diabetes: case-control study and meta-analysis.Semantic proximity Read ↗

The Thr92Ala deiodinase type 2 (DIO2) variant is not associated with type 2 diabetes or indices of insulin resistance in the old order of Amish.Semantic proximity Read ↗

Type 2 deiodinase Thr92Ala polymorphism is associated with disrupted placental activity but not with dysglycemia or adverse gestational outcomes: a genetic association study.Semantic proximity Read ↗

Determination of frequency of Type 2 deiodinase Thr92Ala polymorphism (rs225014) in 131I-treated differentiated thyroid cancer patients undertaking L-Thyroxine (L-T4) suppression therapy.Semantic proximity Read ↗

Type 2 deiodinase Thr92Ala polymorphism is associated with a reduction in bone mineral density: A community-based korean genome and epidemiology study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.