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Article

Type 2 deiodinase Thr92Ala polymorphism is associated with a reduction in bone mineral density: A community-based korean genome and epidemiology study.

Clinical endocrinology - 1 Sept 2020

Kang Yea Eun, Kang Young Mi, Park Boyoung, Shong Minho, Yi Hyon-Seung

Abstract excerpt

OBJECTIVE: Type 2 deiodinase (DIO2)-mediated thyroid hormone synthesis stimulates osteoblast activity and increases the expression of osteoblast differentiation markers, but there are no large cohort studies to identify the role of the DIO2 polymorphism in bone mineral density in humans. METHODS: To investigate the hypothesis that individuals with the DIO2 gene polymorphism are susceptible to osteoporosis, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32324283
DOI: 10.1111/cen.14206

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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