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Article

The Thr92Ala deiodinase type 2 (DIO2) variant is not associated with type 2 diabetes or indices of insulin resistance in the old order of Amish.

Thyroid : official journal of the American Thyroid Association - 1 Nov 2005

Mentuccia Daniela, Thomas Matthew J, Coppotelli Giuseppe, Reinhart Laurie J, Mitchell Braxton D, Shuldiner Alan R, Celi Francesco S

Abstract excerpt

A common polymorphism of the type 2 deiodinase gene (Thr92Ala DIO2) was found to be associated with insulin resistance in a mixed Caucasian population. The aim of this study was to investigate the association of the Thr92Ala DIO2 variant to indices of insulin resistance in the Old Order Amish. A genotype-phenotype association study was performed at the research clinic in Strasburg, Pennsylvania, and the molecular...

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Source

Identifiers

PMID: 16356084
DOI: 10.1089/thy.2005.15.1223

Genes

DIO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The Thr92Ala deiodinase type 2 (DIO2) variant is not associated with type 2 diabetes or indices of insulin resistance in the old order of Amish.PMID 16356084Read ↗

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