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Article

Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects.

The Journal of clinical endocrinology and metabolism - 1 Jan 2007

Grarup Niels, Andersen Mette K, Andreasen Camilla H, Albrechtsen Anders, Borch-Johnsen Knut, Jørgensen Torben, Auwerx Johan, Schmitz Ole, Hansen Torben, Pedersen Oluf

Abstract excerpt

CONTEXT: The type 2 iodothyronine deiodinase (D2) catalyzes the conversion of T(4) to the active form of thyroid hormone, which is a critical regulator of thermogenesis and glucose metabolism. A Thr92Ala polymorphism in the gene encoding D2 (DIO2) has been reported to associate with insulin resistance. OBJECTIVE: The aim of the present study was to assess the impact of the DIO2 Thr92Ala variant on type 2 diabetes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17077128
DOI: 10.1210/jc.2006-1958

Genes

DIO2
ADRB2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects.PMID 17077128Read ↗

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