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Article

Influence of NOS1AP Risk Variants on the Corrected QT (QTc) Interval in the Pharmacotherapy of Schizophrenia.

Pharmacopsychiatry - 1 Sept 2022

Esen-Sehir Dilhan, Kopf Juliane, Hägele Sandra, Plichta Michael M, Reif Andreas, Freudenberg Florian

Abstract excerpt

INTRODUCTION: The variants of the gene for nitric oxide synthase 1 adaptor protein (NOS1AP) are associated with schizophrenia and cardiovascular deficits involving corrected QT (QTc) interval prolongation. Here, we investigated a possible pharmacogenetic effect of antipsychotic treatment on QTc length in interaction with two NOS1AP variants (rs12143842 and rs10494366) whose minor alleles are associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adaptor Proteins, Signal Transducing
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Share to Polymorphism, Single Nucleotide
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Source

Identifiers

PMID: 35732169
DOI: 10.1055/a-1811-7241

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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