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Article

Polymorphisms in the NOS1AP gene modulate QT interval duration and risk of arrhythmias in the long QT syndrome.

Journal of the American College of Cardiology - 15 Jun 2010

Tomás Marta, Napolitano Carlo, De Giuli Luciana, Bloise Raffaella, Subirana Isaac, Malovini Alberto, Bellazzi Riccardo, Arking Dan E, Marban Eduardo, Chakravarti Aravinda, Spooner Peter M, Priori Silvia G

Abstract excerpt

OBJECTIVES: We investigated the role of nitric oxide 1 adaptor protein (NOS1AP) as a genetic modifier of long QT syndrome (LQTS). BACKGROUND: LQTS risk stratification is complicated by the phenotype variability that limits prediction of life-threatening arrhythmic events based on available metrics. Thus, the identification of new markers is desirable. Recent studies have shown that NOS1AP variations in the gene...

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PMID: 20538168
DOI: 10.1016/j.jacc.2009.12.065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Polymorphisms in the NOS1AP gene modulate QT interval duration and risk of arrhythmias in the long QT syndrome.PMID 20538168Read ↗

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NOS1AP Polymorphisms Modify QTc Interval Duration But Not Cardiac Arrest Risk in Hypertrophic Cardiomyopathy.Semantic proximity Read ↗

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