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Article

Genome-wide association study of antipsychotic-induced QTc interval prolongation.

The pharmacogenomics journal - 1 Apr 2012

Aberg K, Adkins D E, Liu Y, McClay J L, Bukszár J, Jia P, Zhao Z, Perkins D, Stroup T S, Lieberman J A, Sullivan P F, van den Oord E J C G

Abstract excerpt

QT prolongation is associated with increased risk of cardiac arrhythmias. Identifying the genetic variants that mediate antipsychotic-induced prolongation may help to minimize this risk, which might prevent the removal of efficacious drugs from the market. We performed candidate gene analysis and five drug-specific genome-wide association studies (GWASs) with 492K single-nucleotide polymorphisms to search for...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 20921969
DOI: 10.1038/tpj.2010.76
PMCID: PMC3388904

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NUBPL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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