Article
Immunofluorescent and molecular characterization of effusion tumor cells reveal cancer site-of-origin and disease-driving mutations.
Cancer cytopathology - 1 Oct 2022
Zhu Yili, Wang Aihui, Allard Grace M, Nordberg Joshua J, Nair Ramesh V, Kunder Christian A, Lowe Alarice C
Abstract excerpt
BACKGROUND: Effective cancer treatment relies on precision diagnostics. In cytology, an accurate diagnosis facilitates the determination of proper therapeutics for patients with cancer. Previously, the authors developed a multiplexed immunofluorescent panel to detect epithelial malignancies from pleural effusion specimens. Their assay reliably distinguished effusion tumor cells (ETCs) from nonmalignant cells;...
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