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Lung adenocarcinoma with malignant serous effusions: A comprehensive clinicopathologic, molecular, and outcome analysis.

Cancer cytopathology - 1 Jun 2026

Ma Weijie, Li Jiannan, Ould Ismail A Aziz, Li Tianhong, Kerr Darcy A, Tafe Laura J, Liu Xiaoying

Abstract excerpt

BACKGROUND: Malignant serous effusions (MSEs), including pleural, pericardial, and peritoneal effusions, are common in advanced lung adenocarcinoma (LUAD). However, integrated clinicopathologic, molecular, treatment, and outcome data across effusion sites remain incompletely defined. METHODS: This study retrospectively analyzed 120 cytology-confirmed LUAD-associated MSE cases from a single academic center by...

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Adenocarcinoma of Lung
Ascitic Fluid
Biomarkers, Tumor
High-Throughput Nucleotide Sequencing
Lung Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pleural Effusion, Malignant

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Identifiers

PMID: 42145151
DOI: 10.1002/cncy.70108

Genes

ALK
BRAF
EGFR
KRAS
ROS1
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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