Article
Molecular genetic alterations in thyroid transcription factor 1-negative lung adenocarcinoma in cytology specimens: A subset with aggressive behavior and a poor prognosis.
Cancer cytopathology - 1 Oct 2018
Rodriguez Erika F, VandenBussche Christopher J, Chowsilpa Sayanan, Maleki Zahra
Abstract excerpt
BACKGROUND: Patients with thyroid transcription factor 1 (TTF1)-negative pulmonary adenocarcinoma (ADC) have been reported to have a worse prognosis and to lack epidermal growth factor receptor (EGFR) mutations. This study describes a series of cytology specimens from patients with clinically confirmed pulmonary carcinoma negative for TTF1. METHODS: A search for TTF1-negative ADC from 2010 to 2017 was performed....
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