Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

From Basics to Benchmarks: Evaluating Sample Adequacy, PD-L1 Expression, and Molecular Profiling in Effusion Samples of Lung Adenocarcinoma.

Diagnostic cytopathology - 1 Aug 2026

Virk Harpreet, Michael Claire, Pfeil Keri Ann, Sadri Navid, Savari Omid, Harbhajanka Aparna

Abstract excerpt

INTRODUCTION: Lung adenocarcinoma commonly causes malignant pleural effusion (MPE), a condition with poor prognosis and limited treatment options. Pleural effusion specimens offer a minimally invasive source for diagnosis and molecular testing. This study evaluates cytologic adequacy for molecular analysis, characterizes mutational and PD-L1 profiles, and correlates findings with survival outcomes. METHODS: Over...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma of Lung
Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged, 80 and over

Share to B7-H1 Antigen

Share to Biomarkers, Tumor

Share to High-Throughput Nucleotide Sequencing

Share to Lung Neoplasms

Share to Pleural Effusion, Malignant

Source

Open in PubMed Open full text

Identifiers

PMID: 42036897
DOI: 10.1002/dc.70132
PMCID: PMC13327414

Genes

TP53
BRAF
EGFR
ALK
KRAS
MET
RET
ROS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

From Basics to Benchmarks: Evaluating Sample Adequacy, PD-L1 Expression, and Molecular Profiling in Effusion Samples of Lung Adenocarcinoma.PMID 42036897Read ↗

Lung adenocarcinoma with malignant serous effusions: A comprehensive clinicopathologic, molecular, and outcome analysis.Semantic proximity Read ↗

High Yield of Pleural Cell-Free DNA for Diagnosis of Oncogenic Mutations in Lung Adenocarcinoma.Semantic proximity Read ↗

Molecular testing in lung cancer: fine-needle aspiration specimen adequacy and test prioritization prior to the CAP/IASLC/AMP Molecular Testing Guideline publication.Semantic proximity Read ↗

Comprehensive Genomic Profiling of Malignant Effusions in Patients with Metastatic Lung Adenocarcinoma.Semantic proximity Read ↗

EGFR testing in paraffin-embedded cell block cytology material is reliable with increased detection for effusion fluid.Semantic proximity Read ↗

Tumor-derived DNA from pleural effusion supernatant as a promising alternative to tumor tissue in genomic profiling of advanced lung cancerSemantic proximity Read ↗

Molecular Profiling of Malignant Pleural Effusions with Next Generation Sequencing (NGS): Evidence that Supports Its Role in Cancer ManagementSemantic proximity Read ↗

Lung cancer cytology and small biopsy specimens: diagnosis, predictive biomarker testing, acquisition, triage, and management.Semantic proximity Read ↗

Molecular profiling of breast cancer pleural effusions using cytology specimens: Impact of sample source and cytological features on next-generation sequencing performance.Semantic proximity Read ↗

Clinicopathological and molecular characterization of non-small cell lung cancer with pericardial effusions.Semantic proximity Read ↗

Feasibility of EBUS-TBNA for histopathological and molecular diagnostics of NSCLC-A retrospective single-center experience.Semantic proximity Read ↗

Liquid-based cytology specimens for next-generation sequencing in lung adenocarcinoma: challenges and evaluation of targeted therapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.