Article
Diagnostic molecular biomarkers for malignant pleural effusions.
Future oncology (London, England) - 1 Jun 2011
Sriram Krishna B, Relan Vandana, Clarke Belinda E, Duhig Edwina E, Yang Ian A, Bowman Rayleen V, Lee Y C Gary, Fong Kwun M
Abstract excerpt
Malignant pleural effusions (MPEs) are a common and important cause of cancer-related mortality and morbidity. Prompt diagnosis using minimally invasive tests is important because the median survival after diagnosis is only 4-9 months. Pleural fluid cytology is pivotal to current MPE diagnostic algorithms but has limited sensitivity (30-60%). Consequently, many patients need to undergo invasive diagnostic tests...
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