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Article

GPR15L is an epithelial inflammation-derived pruritogen

15 Jun 2022

Abstract excerpt

Itch is an unpleasant sensation that often accompanies chronic dermatological conditions. Although many of the itch receptors and the neural pathways underlying this sensation are known, the identity of endogenous ligands is still not fully appreciated. Using an unbiased bioinformatic approach, we identified GPR15L as a candidate pruritogen whose expression is robustly up-regulated in psoriasis and atopic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35704588
DOI: 10.1126/sciadv.abm7342

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